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| Combined screening |
| . |
| First
trimester
Weeks : 11.3 to 13.6
- Free hCG
- PAPP-A
- Ultrasound
(nuchal translucency)
- Detects only chromosomal
abnormalities;
- Result are available early
- Justified is chorionic villous
sampling was available
|
|
|
| Serum screening |
| . |
|
Second
trimester
Weeks : 15 to 20.6
- Free hCG
- InhibineA
- Estrion
- Alpha-fetoprotein
- Detects chromosomal
abnormalities and neural
tube defects
- Result are available later
- Accuracy comparable to the combined
first trimester
screening. This test is ideal if
ultrasound expertise is not
available.
|
|
|
| Integrated screening |
| . |
| It currently offers
the best detection rate with the
fewest unnecessary amniocentesis
This test combines Nuchaltransluency,
the first trimester markers as well as the second
trimester markers. It is performed in two stages.
First trimester - Weeks : 11.3 to
13.6
- This test detects chromosomal
abnormalities and neural tube defects.
Second trimester - Weeks :
15 to 20.6
- This test detects chromosomal
abnormalities and neural tube defects.
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